ICSI With IMSI – What All Should You Know

ICSI With IMSI – What All Should You Know


By Ivf Spring Fertility Centre,

Thanks to the dynamic nature of technology, more and more new techniques and treatments are being introduced in the world of health care, especially in the field of IVF or In Vitro Fertilisation. Every new specialist you meet promises you the latest treatment to help you with 100% successful fertilisation and that is exactly what they offer. Then what is the problem?

The underlying problem here is, with the introduction of every new technique, there is a new name that you have to memorise and a new concept you have to understand. It is here that your mind is lead to the pit of confusion and uncertainty. Consulting with an IVF specialist will help you clear out most to all of these confusions and help you settle on the treatment that will provide you with the best results. In case you are confused as to what ICSI with IMSI is, at the moment, read on to put your doubts to rest.

What is ICSI?
Before we get on to learning more about the compatibility between ICSI and IMSI, it is important that we first learn what both these treatments are. Intracytoplasmic Sperm Injection, more popularly referred to as ICSI is a specific process that abides by the IVF principles, which includes fertilising an egg outside of the uterus of the mother. Here the egg is fertilised by injecting the sperm inside the egg. The process follows as under-

  1. To make this process a success, the biological mother is given medication prescribed by the IVF specialist, in order to increase the all over count of the eggs.
  2. Post medication, constant monitoring is done by the specialist to detect the maturity time of the eggs.
  3. Once they are matured, the eggs are harvested, or in more common term retrieved from the ovary and placed on a dish, designed especially for this process and referred to as the Petri dish.
  4. Once these eggs are inspected under the microscope the healthiest and strongest sperms are chosen from the lot and injected directly into these eggs.

Post the fertilization process, the mature and fertilised eggs are taken and inseminated back inside the uterus.

What is IMSI?
Intracytoplasmic Morphologically-Selected Sperm Injection Process, also popularly referred to as IMSI is the newest variant of ICSI and is another option that couples can opt for. Here, a microscope, much higher in power than the regular one is used to select the sperms with the highest potentiality, health and strength and then injected into the matured eggs. The power of the microscopes, enables the embryogists and the IVF specialists to look deeper into each sperm, to a level where their genetic material is also visible. This process ensures the chances of higher fertilisation compared to its predecessor, the ICSI.

In both cases, the principles of ICSI are followed and executed. The only difference between both the processes is of the calibre of the microscope and the infusion of the genetically strongest and most competent sperms. The choice between the two processes generally depends on the present fertility status of the couple, financial competence and what the doctor deems fit for his/her patient.