The Difference Between PGD and PGS!

The Difference Between PGD and PGS!


By Sneh Hospital,  IVF Speciality

IVF or In Vitro Fertilization is a process that is opted for by couples and individuals who are looking forward to conceiving a baby, which they are unable to do, naturally. The process includes taking the egg from the female and the sperm from the male on a laboratory dish and combining them manually. This combination of the egg and the sperm is then transferred into the mother’s or the bearer’s uterus. The whole process of getting impregnated with the help of IVF takes about four to six weeks. While the extraction of the egg and sperms take only about half a day at the fertilisation clinic, you will again have to come back to the clinic for the transfer of the embryos from the lab dish to inside the uterus, between a time span of 2 to 6 days.

IVF and ancillary processes:

While IVF or In Vitro Fertilization is the mother of the artificial fertilisation, there are other processes that are ancillary to it and are necessary to make the process a 100% success. Some of these processes include-

  • PGD or Pre-implantation Genetic Diagnosis, and
  • PGS or Pre-implantation Genetic Screening

A lot of people opting for IVF are confused between the two processes and have a tough time discerning their importance. This confusion and misleading myths also lead to a number of misunderstandings amongst the patients. Read on to find the difference between PGD and PGS.

PGD or Pre-implantation Genetic Diagnosis:

The main motive of Preimplantation Genetic Diagnosis (PGD) involves the diagnosis of every single cell present in the embryos in order to detect any kind of chromosomal disorder or other genetic diseases. This helps in making sure that the child to be born is not born with any kind of disease, ailment or for that matter any kind of minor or major disorder. The PGD is a process that is paired with the IVF. Any individual or couple, going for an IVF has to take the PGD, prior to the IVF. Hence, this phase takes place post the retrieval of the eggs and the sperms and before the embryos are transferred to the uterus, in order to establish a pregnancy.

  1. What this process does, is allows the parent/s to choose the embryos based on their PGD and chromosomal status and ensure a healthy life for their, to be born baby.
  2. It eliminates the chances for unsuccessful impregnation,
  3. It identifies abnormal or weak embryos, and most importantly
  4. Leaves behind, identifying the fittest and healthy embryos to be transferred to the uterus.

Other than these, the PGD also detects chromosomal translocations and single gene disorders, such as- Tay Sachs, Cystic Fibrosis, Myotonic Dystrophy, Fragile X and Thalassemia.

PGS or Pre-implantation Genetic Screening:

For a couple who have been scarred with the memory of multiple pregnancy losses or constant infertility issues, PGS is of optimum importance. The process follows right after PGD and leads to the final wing of embryo transfer. The main role of PGS is to use the information extended by PGD and use the same to appoint efficient treatment, in order to improve the chances of pregnancy by detecting any kind of chromosomal abnormality.

Hence, now that you know what both these tests are meant for, it must also be clear to you as to how both of them are necessary for a successful IVF. Consulting well known IVF specialists will help you learn about these processes in details and also get the best help out of them.